Albert Y. Cheung, MD,*† Joshua H. Hou, MD,‡§ Peter Bedard, MS,‡ Veronique Grimes, CEBT, COMT,‡ Natalie Buckman, BA,‡ Medi Eslani, MD,* and Edward J. Holland, MD*

Endothelial keratoplasty procedures, such as Descemet membrane endothelial keratoplasty (DMEK) and Desce- met stripping automated endothelial keratoplasty (DSAEK), have become the preferred treatment for endothelial dysfunc- tion and disease as they allow selective replacement of the diseased endothelium.1 Although DMEK has grown in popularity because it provides true anatomic replacement of recipient diseased Descemet membrane and endothelium,2 surgical difficulty and unpredictability associated with the procedure have limited its widespread adoption. As a result, DSAEK remains the most popular endothelial keratoplasty technique in the United States.

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